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Ionotropic glutamate receptor that features being a cation permeable ligand-gated ion channel, gated by L-glutamate as well as glutamatergic agonist kainic acid. L-glutamate functions as an excitatory neurotransmitter at a lot of synapses during the central anxious system. Binding from the excitatory neurotransmitter L-glutamate induces a conformat